Possible Wintour appointment gets London talking

LONDON (AP) — Thomas Jefferson, Ben Franklin, John Quincy Adams ... and now Anna Wintour?

A report suggesting that the influential editor-in-chief of Vogue is one of the candidates being considered for the top U.S. diplomatic post in France or Britain has sparked spirited debate about her qualifications, exciting Britain's glamour-hungry tabloids but raising hackles at the conservative Daily Telegraph.

"Anna Wintour may be an enticing pick for a celebrity-fixated White House," wrote Nile Gardner in the Telegraph. "But she is eminently unsuitable for America's most prestigious diplomatic posting."

The possibility that the British-born Wintour would move into London's grand ambassadorial residence was raised several years ago by The Guardian newspaper — where her brother Patrick is a prominent journalist — and again this week by Bloomberg News, which based its report on "two people familiar with the matter."

Officials at the U.S. Embassy in London said they would not speculate on President Obama's eventual choice for a successor to Ambassador Louis Susman, who has announced plans to step down. White House officials have also refused to comment.

Officials caution that a decision is months away and would only follow the appointment of a new secretary of state to replace outgoing Hillary Clinton and would also include a thorough vetting process.

Guardian fashion writer Jess Cartner-Morley said the editor — the model for the imperious character played by Meryl Streep in "The Devil Wears Prada" movie — would be well-suited for an ambassadorial position.

"Wintour is generally acknowledged as whipsmart and extremely hard-working," she wrote. "She is enormously charismatic, a born networker and a formidable fundraiser."

Cartner-Morley also challenged the dismissive view that Wintour's many years in the fashion industry are not enough, citing recent ambassadorial choices of a retired investment banker and a retired car dealership owner.

"Is a career as one of the biggest global players in an industry estimated to be worth $900 billion to the world economy really so inferior and shallow by comparison?" the writer asked.

Vogue spokeswoman Megan Salt in New York said Wednesday said that Wintour is very happy with her present job.

Wintour raised $40 million for Obama's re-election through a number of campaigns and star-studded dinners she co-hosted with some of the most powerful people in the entertainment and fashion worlds. In August, she teamed up with movie mogul Harvey Weinstein for a fundraising dinner, after a successful party at Sarah Jessica Parker's Manhattan home in July.

The ambassadorial posts in France and Britain — formally known as the Court of St. James's — are among the most coveted in the diplomatic ranks. They also typically go to wealthy individuals willing to use personal funds to buttress the government-provided entertainment budget.

Wintour, 63, is best-known for her trademark glossy bob hairstyle, oversized sunglasses and haughty demeanor. Born in London, she started in fashion journalism at Harper's Bazaar and New York magazine, and after working at the helm of other glossies became editor-in-chief at U.S. Vogue in 1988.

Carne Ross, a former British diplomat who now runs a New York-based diplomatic advisory group, said Wintour's skills — "honed in the vicious world of the fashion industry" — would qualify her for a diplomatic posting.

Ross said a large part of an ambassador's job involves taking part in social gatherings, something Wintour would be comfortable with. Often most of the real political work is done by direct communications between the White House and the prime minister's office at Downing Street, he said.

"That diminishes the political significance of the ambassador's role," he said.

Mary Jo Jacobi, a presidential adviser during two Republican administrations, said Wintour would be an unusual choice but possibly an effective one.

"Vogue is a very successful, very large publication, and she has experience with big budgets and with challenging, difficult people," Jacobi said. "She knows how to marshal resources. And her job has involved a great deal of diplomacy."

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Longer tamoxifen use cuts breast cancer deaths

Breast cancer patients taking the drug tamoxifen can cut their chances of having the disease come back or kill them if they stay on the pills for 10 years instead of five years as doctors recommend now, a major study finds.

The results could change treatment, especially for younger women. The findings are a surprise because earlier research suggested that taking the hormone-blocking drug for longer than five years didn't help and might even be harmful.

In the new study, researchers found that women who took tamoxifen for 10 years lowered their risk of a recurrence by 25 percent and of dying of breast cancer by 29 percent compared to those who took the pills for just five years.

In absolute terms, continuing on tamoxifen kept three additional women out of every 100 from dying of breast cancer within five to 14 years from when their disease was diagnosed. When added to the benefit from the first five years of use, a decade of tamoxifen can cut breast cancer mortality in half during the second decade after diagnosis, researchers estimate.

Some women balk at taking a preventive drug for so long, but for those at high risk of a recurrence, "this will be a convincer that they should continue," said Dr. Peter Ravdin, director of the breast cancer program at the UT Health Science Center in San Antonio.

He reviewed results of the study, which was being presented Wednesday at a breast cancer conference in San Antonio and published by the British medical journal Lancet.

"The result of this trial will have a major, immediate impact on premenopausal women," Ravdin said.

About 50,000 of the roughly 230,000 new cases of breast cancer in the United States each year occur in women before menopause. Most breast cancers are fueled by estrogen, and hormone blockers are known to cut the risk of recurrence in such cases.

Tamoxifen long was the top choice, but newer drugs called aromatase inhibitors — sold as Arimidex, Femara, Aromasin and in generic form — do the job with less risk of causing uterine cancer and other problems.

But the newer drugs don't work well before menopause. Even some women past menopause choose tamoxifen over the newer drugs, which cost more and have different side effects such as joint pain, bone loss and sexual problems.

The new study aimed to see whether over a very long time, longer treatment with tamoxifen could help.

Dr. Christina Davies of the University of Oxford in England and other researchers assigned 6,846 women who already had taken tamoxifen for five years to either stay on it or take dummy pills for another five years.

Researchers saw little difference in the groups five to nine years after diagnosis. But beyond that time, 15 percent of women who had stopped taking tamoxifen after five years had died of breast cancer versus 12 percent of those who took it for 10 years. Cancer had returned in 25 percent of women on the shorter treatment versus 21 percent of those treated longer.

Tamoxifen had some troubling side effects: Longer use nearly doubled the risk of endometrial cancer. But it rarely proved fatal, and there was no increased risk among premenopausal women in the study — the very group tamoxifen helps most.

"Overall the benefits of extended tamoxifen seemed to outweigh the risks substantially," Dr. Trevor Powles of the Cancer Centre London wrote in an editorial published with the study.

The study was sponsored by cancer research organizations in Britain and Europe, the United States Army, and AstraZeneca PLC, which makes Nolvadex, a brand of tamoxifen, which also is sold as a generic for 10 to 50 cents a day. Brand-name versions of the newer hormone blockers, aromatase inhibitors, are $300 or more per month, but generics are available for much less.

The results pose a quandary for breast cancer patients past menopause and those who become menopausal because of their treatment — the vast majority of cases. Previous studies found that starting on one of the newer hormone blockers led to fewer relapses than initial treatment with tamoxifen did.

Another study found that switching to one of the new drugs after five years of tamoxifen cut the risk of breast cancer recurrence nearly in half — more than what was seen in the new study of 10 years of tamoxifen.

"For postmenopausal women, the data still remain much stronger at this point for a switch to an aromatase inhibitor," said that study's leader, Dr. Paul Goss of Massachusetts General Hospital. He has been a paid speaker for a company that makes one of those drugs.

Women in his study have not been followed long enough to see whether switching cuts deaths from breast cancer, as 10 years of tamoxifen did. Results are expected in about a year.

The cancer conference is sponsored by the American Association for Cancer Research, Baylor College of Medicine and the UT Health Science Center.

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Dems call Republicans 'hostage takers' on debt talks

Screen shot from GOPHostageTakers.com

House Democrats on Wednesday launched a new microsite, GOPHostageTakers.com, criticizing Republican leaders for not holding a vote to exclusively extend middle-income tax rates for another year as part of avoiding the so-called fiscal cliff.

Current tax rates for all income levels are set to automatically increase in 2013 unless Congress takes action this year. Most Republicans want to extend the current rates for all income levels, while Democrats want taxes to increase for households earning more than $250,000 annually.

The Democratic Congressional Campaign Committee launched the site as part of a larger messaging effort to goad Republicans into voting on a bill that excludes those earning more than $250,000 from the rate extension.

This week, House Minority Leader Nancy Pelosi, a California Democrat, submitted a "discharge petition" that would force a vote on a bill to extend rates only for middle-class taxpayers, but only if she can persuade 218 members of the Republican-led House to sign it. (Realistically, it's unlikely.) On the microsite, House Democrats list the names of some Republicans they consider "vulnerable" who have declined to sign Pelosi's petition.

Earlier this year, the Republican-led House approved a bill to extend tax rates for all income brackets while the Democrat-controlled Senate passed a measure that extends them for households under the $250,000 level.

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Powerful typhoon kills at least 74 in Philippines

MANILA, Philippines (AP) — At least 43 villagers and soldiers drowned in a southern Philippine town Tuesday when torrents of water dumped by a powerful typhoon cascaded down a mountain, engulfing emergency shelters and an army truck, officials said. The deaths raised the toll from one of the strongest storms to hit the country this year to at least 74.

Gov. Arturo Uy said rain from Typhoon Bopha accumulated atop a mountain and then burst down on Andap village in New Bataan town in hard-hit Compostela Valley province. The victims included villagers who had fled from their homes to a school and village hall, which were then swamped by the flash flood. An army truck carrying soldiers and villagers was washed away, according to Uy and army officials.

"They thought that they were already secure in a safe area, but they didn't know the torrents of water would go their way," Uy told DZBB radio.

He said the confirmed death toll in the town was likely to rise because several other bodies could not immediately be retrieved from floodwaters strewn with huge logs and debris.

Bopha slammed into Davao Oriental province region at dawn, its ferocious winds ripping roofs from homes and its 500-kilometer (310-mile) -wide rain band flooding low-lying farmland.

The storm, packing winds of 140 kilometers (87 miles) per hour and gusts of up to 170 kph (106 mph), toppled trees, triggered landslides and sent flash floods surging across the region's mountains and valleys.

Two entire provinces lost power and more than 100 domestic flights were canceled. About 60,000 people fled to emergency shelters.

Twenty-three people drowned or were pinned by fallen trees or collapsed houses in Davao Oriental province's coastal town of Cateel, which had the most deaths after New Bataan, Davao Oriental Gov. Corazon Malanyaon told the ABS-CBN TV network, citing police reports.

Some towns in the province were so battered that no roofs remained on buildings, Malanyaon said.

The other deaths included three children who were buried by a wall of mud and boulders that plunged down a mountain in Marapat village, also in Compostela Valley. Their bodies were wrapped in blankets by their grieving relatives and placed on a stage in a basketball court.

"The only thing we could do was to save ourselves. It was too late for us to rescue them," said Valentin Pabilana, who survived the landslide.

In Davao Oriental, a poor agricultural and gold-mining province about 1,000 kilometers (620 miles) southeast of Manila, an elderly woman was killed when her house was struck by a falling tree, said Benito Ramos, who heads the government's disaster-response agency.

The other victims either drowned or were hit by trees, he said, adding that the death toll was expected to rise.

While some 20 typhoons and storms normally lash the archipelago nation annually, the southern provinces battered by Bopha are unaccustomed to fierce typhoons, which normally hit the northern and central Philippines.

A rare storm last December killed more than 1,200 people and left many more homeless and traumatized, including in Cagayan de Oro city, where church bells pealed relentlessly on Tuesday to warn residents to scramble to safety as a major river started to swell.

Officials were taking no chances this year, and President Benigno Aquino III appealed on national TV on Monday for people in Bopha's path to move to safety and take storm warnings seriously.

In Compostela Valley, authorities halted mining operations and ordered villagers to evacuate to prevent a repeat of deadly losses from landslides and the collapse of mine tunnels in previous storms.

Bopha, a Cambodian word for flower or a girl, is the 16th weather disturbance to hit the Philippines this year. Forecasters say at least one more storm may strike the country before Christmas.

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Associated Press writer Teresa Cerojano contributed to this report.

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China goes crazy for iPhone 5: Preorders hit 100,000 units in under 24 hours

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Royal pregnancy highlights succession issues

LONDON (AP) — The business of monarchy has always been stacked in favor of men. Not any more — or so the British government promises.

The first child of Prince William and his wife Kate will be born a king or a queen in waiting, under changes to succession rules designed to overturn centuries of tradition and give royal daughters the same rights as sons.

Deputy Prime Minister Nick Clegg pledged Tuesday that the law on succession would be changed at the "earliest opportunity." He said "whether the baby is a boy or a girl, they will have an equal claim to the throne."

"Born to rule, be it a boy or a girl" proclaimed the Daily Mail, which noted that the baby had "already made royal and constitutional history" even before it is born.

Not so fast, caution others.

A royal saga needs a touch of uncertainty, and experts point out that despite politicians' promises, the law giving males primacy in succession has not yet been changed — and the clock is ticking.

"We know that the wishes of politicians are written in water," said royal historian Robert Lacey. "Law only becomes law when the law is made — and the law has not been made."

Meanwhile, the Duchess of Cambridge — the former Kate Middleton — was "continuing to feel better" Tuesday as she spent a second day in a London hospital being treated for acute morning sickness, St. James's Palace said. Photographers and camera crews from around the world camped outside, eager for news on the royal pregnancy. Officials said earlier the duchess was not yet 12 weeks pregnant.

Congratulations poured in from around the world at the good news, which follows Kate and William's lavish royal wedding in 2011 and Queen Elizabeth II's Diamond Jubilee celebrations this year.

Officials say Kate and William's baby will displace Prince Harry, William's younger brother, as third in line to the throne — and the child will stay there, even if she is a princess who later acquires a younger brother.

For centuries, preference was given to male heirs, so a first-born princess would be leapfrogged in the succession by a younger brother. As a result, there have been some 40 kings of England since the Norman Conquest in 1066, but only seven queens.

Last year, the leaders of Britain and the 15 former colonies that have the queen as their head of state informally agreed to establish new rules giving female children equal status with males in the order of succession — something that will require legal changes in each country.

"Put simply, if the Duke and Duchess of Cambridge were to have a little girl, that girl would one day be our queen," Prime Minister David Cameron said at the time.

Months passed with little progress. But the prospect of a royal birth next year seems to have focused political minds, at least somewhat: Clegg announced Tuesday that all 16 nations had now formally agreed to change their laws.

Clegg also said a Succession to the Crown Bill would be introduced in Britain's House of Commons as soon as the parliamentary schedule permits.

"Notwithstanding a few parliamentary turns of the wheel, this is now going to happen," Clegg said, adding that "the old-fashioned rules ... have been swept aside."

In Britain, implementing the new rule means changing bits of several key constitutional documents, including the Bill of Rights and Coronation Oath Act of 1688, the 1701 Act of Settlement and the 1706 Act of Union with Scotland.

Lacey said if it is not done by the time the baby is born, uncertainty is bound to remain. A first-born girl could find her younger brother challenging her for the throne on the grounds that the law had not been changed at the time of her birth.

And what if Kate has twins? Experts say the firstborn will be the heir — but things could get complicated if the succession rules are not changed before the birth.

"Say they have twins and a girl comes out first and 20 years later the boy turns out to be the more attractive character," Lacey said. "People will say that at the time the law meant the boy should have inherited."

Rebecca Probert, a professor at the University of Warwick's school of law, said there are other issues that the law should address to bring the monarchy up to date.

British monarchs are banned from marrying Roman Catholics, but not members of other faiths — something Clegg said the new law would change.

An heir also cannot marry without the monarch's permission, and can't marry in a civil ceremony — even though Prince Charles, William's father, did just that when he wed his second wife, Camilla Parker Bowles, in 2005.

Probert said it's important "to have a clause in there confirming that monarchs are able to marry in the same ways that are open to their subjects."

But she thinks that may prove too complicated for lawmakers in the short term.

"They might decide in the interests of time to stick to the single issue of gender and leave the rest to a more convenient time — which tends to be never," she said.

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Jill Lawless can be reached on http://Twitter.com/JillLawless

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CDC says US flu season starts early, could be bad

NEW YORK (AP) — Flu season in the U.S. is off to its earliest start in nearly a decade — and it could be a bad one.

Health officials on Monday said suspected flu cases have jumped in five Southern states, and the primary strain circulating tends to make people sicker than other types. It is particularly hard on the elderly.

"It looks like it's shaping up to be a bad flu season, but only time will tell," said Dr. Thomas Frieden, director of the Centers for Disease Control and Prevention.

The good news is that the nation seems fairly well prepared, Frieden said. More than a third of Americans have been vaccinated, and the vaccine formulated for this year is well-matched to the strains of the virus seen so far, CDC officials said.

Higher-than-normal reports of flu have come in from Alabama, Louisiana, Mississippi, Tennessee and Texas. An uptick like this usually doesn't happen until after Christmas. Flu-related hospitalizations are also rising earlier than usual, and there have already been two deaths in children.

Hospitals and urgent care centers in northern Alabama have been bustling. "Fortunately, the cases have been relatively mild," said Dr. Henry Wang, an emergency medicine physician at the University of Alabama at Birmingham.

Parts of Georgia have seen a boom in traffic, too. It's not clear why the flu is showing up so early, or how long it will stay.

"My advice is: Get the vaccine now," said Dr. James Steinberg, an Emory University infectious diseases specialist in Atlanta.

The last time a conventional flu season started this early was the winter of 2003-04, which proved to be one of the most lethal seasons in the past 35 years, with more than 48,000 deaths. The dominant type of flu back then was the same one seen this year.

One key difference between then and now: In 2003-04, the vaccine was poorly matched to the predominant flu strain. Also, there's more vaccine now, and vaccination rates have risen for the general public and for key groups such as pregnant women and health care workers.

An estimated 112 million Americans have been vaccinated so far, the CDC said. Flu vaccinations are recommended for everyone 6 months or older.

On average, about 24,000 Americans die each flu season, according to the CDC.

Flu usually peaks in midwinter. Symptoms can include fever, cough, runny nose, head and body aches and fatigue. Some people also suffer vomiting and diarrhea, and some develop pneumonia or other severe complications.

A strain of swine flu that hit in 2009 caused a wave of cases in the spring and then again in the early fall. But that was considered a unique type of flu, distinct from the conventional strains that circulate every year.

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Online:

CDC: http://www.cdc.gov/flu/weekly

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Conservative Republicans booted from House budget panel

WASHINGTON (Reuters) - Two of the most conservative Republicans in the House of Representatives have been kicked off the House Budget Committee, a rare move that could make it easier for the panel to advance a deal with Democrats to cut fiscal deficits.

Representatives Tim Huelskamp of Kansas and Justin Amash of Michigan - both favorites of the anti-tax Tea Party movement - are among those Republicans voting most often against House Speaker John Boehner.

Huelskamp and Amash, who both will begin second terms in the House next month, voted against last year's deal to raise the federal debt limit and staunchly oppose any tax increases. Boehner has now included new revenue in his latest offer to avert the "fiscal cliff" of year-end tax hikes and automatic spending cuts. Given their voting records, winning support from Huelskamp and Amash for such a compromise seemed an uphill battle.

Huelskamp released a statement saying the Republican leadership "might think they have silenced conservatives but removing me and others from key committees only confirms our conservative convictions.

"This is clearly a vindictive move and a sure sign that the GOP establishment cannot handle disagreement," he said.

Huelskamp and Amash had said that despite sweeping changes to the Medicare and Medicaid healthcare programs, committee chairman Paul Ryan's budget did not make deep enough cuts to entitlement programs and military spending.

Boehner spokesman Michael Steel declined to be specific on the reasons for their ouster by the House Republican Steering Committee, which occurred Monday in a closed-door meeting.

"The Steering Committee makes decisions based on a range of factors," Steel said.

Huelskamp said he was given "limited explanation" for his removal from the Budget Committee, a move he called "vindictive." A spokesman for Amash could not be immediately reached for comment.

Huelskamp and Amash cast the only House Budget Committee votes against Ryan's budget plan earlier this year.

While there is often wrangling over committee chairmanships just before a new Congress takes office, it is rare for rank-and-file committee members to be stripped of their assignments.

The 34-member Republican steering committee is headed by Boehner and includes members of House leadership, committee chairs and other lawmakers representing different regions of the country.

The same group last week recommended that Ryan, the conservative former Republican vice presidential candidate, be renewed as Budget Committee chairman.

(Editing by Bill Trott)

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Gunman severely wounds Swedish woman in Pakistan

LAHORE, Pakistan (AP) — A gunman on a motorcycle shot and severely wounded an elderly Swedish woman who worked at a church in eastern Pakistan on Monday, officials said.

The woman, who was identified by Pakistani police as Bargetta Emmi, was getting out of her car in front of her home in the city of Lahore when she was shot in the neck by an unknown assailant. Her servants reported the incident to police, said Pakistani police officer Malik Awais.

She was a director of FGA Church (Full Gospel Assemblies of Pakistan), Awais said.

Swedish Foreign Ministry spokesman Teo Zetterman confirmed en elderly Swedish woman was shot and severely wounded in Lahore. He said she was a volunteer worker in her 70s, but did not provide her name or where she worked.

The woman is a Swedish citizen but has lived and worked in Pakistan for several years, said Zetterman.

The gunman who shot Emmi escaped, and the motive was unclear.

Also in Lahore, gunmen on Monday desecrated over 100 graves of Ahmadis, members of a persecuted religious sect in Pakistan, said Awais, the police officer. More than a dozen gunmen held the caretakers of the graveyard hostage while they defaced the graves.

"You can't inscribe verses from the holy Quran on the graves. You are Ahmadis. You are not Muslims," one of the attackers told the caretakers, according to Awais.

Parliament amended Pakistan's constitution in 1974 to declare that Ahmadis were not considered Muslims under the law.

Ahmadis believe their spiritual leader, Hadrat Mirza Ghulam Ahmad, who died in 1908, was a messiah — a position rejected by the government in response to a mass movement led by Pakistan's major Islamic parties.

The Ahmadis' plight — along with that of Pakistan's other religious minorities, such as Shiite Muslims, Christians and Hindus — has deepened in recent years as hard-line interpretations of Islam have gained ground and militants have stepped up attacks against groups they oppose. Most Pakistanis are Sunni Muslims.

Also Monday, a roadside bomb ripped through a police van as it was patrolling on the outskirts of the northwestern city of Peshawar, killing two officers and wounding two others, said senior police officer Javed Khan.

Peshwar is on the edge of Pakistan's tribal region, the main sanctuary for Taliban militants in the country, and has been hit by frequent bombings over the past few years.

In the southern city of Karachi, a gunman riding on a motorcycle killed the leader of an Islamic seminary, sparking a riot by hundreds of seminary students, who stoned shops and set vehicles on fire, said police officer Azhar Iqbal.

Karachi has a long history of political, sectarian and ethnic strife, which has been on the rise this year.

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Associated Press writers Louise Nordstrom in Stockholm, Adil Jawad in Karachi, Pakistan and Sebastian Abbot in Islamabad contributed to this report.

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Obama Is Taking Himself and #My2K to Twitter This Afternoon

What a day for Twitter! First the Pope, then the Royal Baby, and now President Obama will come online to answer questions about the fiscal cliff. A @WhiteHouse tweet with the distincitive “-bo” signature, announced not long ago that the big guy himself will be taking questions online, starting at 2:00 p.m. ET.

Good to see lots of folks on twitter speaking out on extending middle class tax cuts. I’ll answer some Qs on that at 2ET. Ask w/ #My2k –bo

— The White House (@whitehouse) December 3, 2012

Unfortunately, he’s sticking with the troublesome #My2K hashtag that conservatives have already seized upon in a back-and-forth battle for messaging. Trying to mobilize your supporters through social media is all well and good, but the problem with any genuinely open town hall, is that anyone can invite themselves—even those who disagree with you and might be louder than your friends. (Plus, any reasonably popular hashtag moves much to fast for anyone to follow it or have an actual conversation on Twitter anyway.)

RELATED: Don’t Expect Too Much From Social Media Town Halls

But ask away! Maybe you’ll get luck and get RT’d by the President himself. And then find yourself becoming the next conservative meme as soon as the hashtag-averse pundits start making fun of your question. Should be a fun afternoon.

Social Media News Headlines – Yahoo! News

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